RAF Typhoon FGR4s have conducted a mission with France's air force in a combined operation on an hidden munitions depot in Syria employed by the Daesh militant organization, as stated by the UK Ministry of Defence.
The location, located using reconnaissance, was thought to be storing arms and explosives, the statement said, and was positioned in mountains just above Palmyra in Syria's central region.
"Our aircraft used laser-guided Paveway IV weapons to hit a series of entry passages leading to the depot... early reports suggest the strike was effective," the MoD said.
There was no evidence of any civilian impact in the operation conducted Saturday night and all the aircraft returned to base without incident, the defence officials confirmed.
The British jets were supported by a Voyager tanker plane.
Daesh - alternatively referred to as Daesh - imposed militant control over parts of Iraq and Syria until 2019.
"This action demonstrates our UK leadership, and commitment to stand shoulder to shoulder with allied nations, to stamp out any re-emergence of IS and their dangerous and violent ideologies in the Middle East," UK Defence Secretary the minister remarked.
RAF aircraft have conducted overwatch operations over Syrian airspace to "forestall any attempted comeback" of Islamic State following its defeat at the climactic battle in Baghuz in 2019, the MoD reported.
"I extend gratitude to the personnel of the UK armed forces who took part in this mission for their expertise and their valour," he added. "They were among a great many British personnel stationed over the festive period. This mission, to eliminate militants who pose a risk to our safety, highlights how British military are ready to step up, throughout the year, keeping Britain secure within its borders and powerful internationally."
Last December, the United States armed forces executed what it termed a "major assault" targeting IS targets in the country, after an assault killed two US servicemembers and a civilian interpreter in the Palmyra area.
The United Nations estimates IS still maintains an estimated 5,000 to 7,000 fighters in Syria and Iraq.